Journal: Pharmaceutics

Article Title: Neuronanomedicine: An Up-to-Date Overview

doi: 10.3390/pharmaceutics11030101

Figure Lengend Snippet: The main advantages, disadvantages, and surface functionalization strategies for the organic and inorganic nanocarriers.

Article Snippet: Stroke , poly(lactic- co -glycolic) acid nanoparticles , chlorotoxin , Lexiscan and Nogo-66 , in vivo—male C57BL/6 mice , [ ] .

Techniques: Permeability

Journal: Pharmaceutics

Article Title: Neuronanomedicine: An Up-to-Date Overview

doi: 10.3390/pharmaceutics11030101

Figure Lengend Snippet: A summary of the nanotechnology-based treatment strategies for brain cancer, neurodegenerative diseases, and stroke.

Article Snippet: Stroke , poly(lactic- co -glycolic) acid nanoparticles , chlorotoxin , Lexiscan and Nogo-66 , in vivo—male C57BL/6 mice , [ ] .

Techniques: In Vivo, Mouse Assay, Transgenic Assay

Journal: Journal of Toxicology

Article Title: Scorpion Peptides: Potential Use for New Drug Development

doi: 10.1155/2013/958797

Figure Lengend Snippet: Schematic proposed models for scorpion toxins use in cancer and metastasis therapy. Scorpion toxins are dotted with high specificity to targeted specific cells receptors enabling them to be potent candidate for drugs carrier. (a) Radioactive iodine delivery into brain gliomas using chlorotoxin as a guider to target cancerous cells. (b) The chlorotoxin triggers gene transfection for cancer cells therapy. (c) Direct effect of pertussis toxin in abolishing metastasis. It did inhibit migration (evasion) through blocking the transduction signal of the lysophosphatidic acid pathway.

Article Snippet: Veiseh and her colleagues [ – ] examined the utility of the chlorotoxin as a nanovector carrier for gene transfection into both C6 glioma and DAOY medulloblastoma cells and improved its effectiveness as a good tool for clinical use ( ) [ , ].

Techniques: Transfection, Migration, Blocking Assay, Transduction

Journal: Journal of Toxicology

Article Title: Scorpion Peptides: Potential Use for New Drug Development

doi: 10.1155/2013/958797

Figure Lengend Snippet: Summary of the modus operandi of some scorpion derivatives with potential therapeutic use.

Article Snippet: Veiseh and her colleagues [ – ] examined the utility of the chlorotoxin as a nanovector carrier for gene transfection into both C6 glioma and DAOY medulloblastoma cells and improved its effectiveness as a good tool for clinical use ( ) [ , ].

Techniques: Activation Assay, Chemotaxis Assay, Activity Assay, Inhibition, Recombinant, Marker